Urolithin A 8-Methyl Ether

April 8, 2021

Urolithins minangka metabolit sekunder saka asam ellagic sing asale saka ellagitannins. Ing manungsa ellagitannins diowahi dening mikroflora usus dadi asam ellagic sing luwih owah dadi urolithins A, urolithin B, urolithin C lan urolithin D ing usus gedhe.

Urolithin video 8-Methyl Ether (35233-17-1)

 

Urolithin A 8-Methyl Ether (35233-17-1)specifications

Jeneng Product Urolithin bubuk 8-Methyl Ether
Jeneng Kimia 3-hidroksi-8-methoxy-6H-benzo [c] chromen-6-siji;

3-hidroksi-8-methoxybenzo [c] chromen-6-siji;

35233-17-1;

MLS001049096;

SMR000386929;

ChemDiv3_002724;

Urolithin A 8-Methyl Ether;

CAS Number 35233-17-1
InChIKey IGJLBTGXYKPECW-UHFFFAOYSA-N
Molekul Formula C14H10O4
Molekul Wwolung 242.23
Monoisotopic Mass 242.057909 g / mol
Titik lebur 242 ° C (Solv: asam asetik (64-19-7))
Titik nggodhok  479.9 ± 38.0 ° C (Diwasa)
Density 1.375 ± 0.06 g / cm3 (Ramalan)
Biologi Half-Life N / A
Werna Krim Beige nganti Oranye Jingga Peteng banget
Skeabsahan  Acetone (Rada, Sonicated) DMSO (Rada, Sonicated), Methanol (Rada)
Storage Temperature  Hygroscopic, -20 ° C Freezer, Ing atmosfer inert
Application Urolithin A 8-Methyl Ether minangka penengah ing sintesis Urolithin A (U847000), metabolit utama Ellagitannin lan nuduhake sifat anti-inflamasi lan antioksidan.

 

reference

[1] Espín, Juan Carlos; Larrosa, Mar; García-Conesa, María Teresa; Tomás-Barberán, Francisco (2013). "Pinunjul Biologis Urolithins, Metabolit Asam Ellagic Gut Mikroutat Gut: Bukti Saiki." Pangobatan Komplementary lan Alternatif Berbasis Bukti. 2013: 270418. doi: 1155/2013/270418. ISSN1741-427X. PMC 3679724. PMID 23781257.

[2] Ryu, Dongryeol; Mouchiroud, Laurent; Andreux, Pénélope A; Katsyuba, Elena; Moullan, Norman; Nicolet-dit-Félix, Amandine A; Williams, Evan G; Jha, Pooja; Sasso, Giuseppe Lo (2016). "Urolithin A nyebabake mitofagy lan ndawakake umure ing C. elegan lan nambah fungsi otot ing tikus". Pengobatan Alam. 22 (8): 879-888. doi: 1038 / nm.4132. PMID 27400265.

[3] Ishimoto, Hidekazu; Shibata, Mari; Myojin, Yuki; Ito, Hideyuki; Sugimoto, Yukio; Tai, Akihiro; Hatano, Tsutomu (2011). "Ing sipat anti-inflamasi lan antioksidan saka ellagitannin metabolit urolithin A" (PDF). Huruf Kimia Organik & Obat. 21 (19): 5901-5904. doi: 1016 / j.bmcl.2011.07.086. PMID 21843938.

[4] Kasimsetty, SG, dkk .: J. Agri. Panganan Chem., 58, 2180 (2010);

[5] Bialonska, D., dkk.: J. Agri. Panganan Chem., 57, 10181 (2009);